Statins ntawm lub xeem tiam

Cov kab mob ntawm cov kab mob hauv plab yog tam sim no suav hais tias yog ib qho tseem ceeb hauv kev ua neej nyob. Nws tsis tau hais tias kom muaj qib roj cholesterol hauv cov ntshav yog qhov tseem ceeb ntawm txhua yam teeb meem ntawm lub plawv, tab sis qhov tseeb tias cov tshuaj no cuam tshuam rau lub cev tsis zoo heev yog qhov tseeb undeniable. Statins ntawm lub xeem tiam, raws li lawv cov thawjcuam, yog npaj tshwj xeeb los mus sib ntaus sib tua roj cholesterol. Rau ib hom neeg ntawm cov neeg mob, cov tshuaj no yog ib hom kev pab cuam.

Leej twg yog tus tshiab statins?

Lub hom phiaj tseem ceeb ntawm statin siv yeeb siv tshuaj yog los tiv thaiv ntau qhov muaj zog ntawm cov enzymes tsim nyog rau tsim cov roj cholesterol hauv lub cev. Cov tshuaj no tuaj yeem txo cov kev sib txawv ntawm cov roj cholesterol (tsawg-density lipoprotein). Yuav luag tag nrho statins ua hauj lwm tib yam - lawv thaiv cov synthesis ntawm teeb meem tshuaj nyob rau hauv lub siab.

Cov xwm txheej ntawm lub xeem tiam thiab lawv cov thawjcuam tau raug tsa los ntawm cov rooj plaub hauv qab no:

  1. Cov neeg laus yog cov muaj teeb meem. Yog li, feem ntau ntawm lawv statins yuav tuaj nyob rau hauv muab rau hauv xwb.
  2. Saib xyuas lub cev nrog cov tshuaj no yuav tsum muaj ntshav qab zib thiab lwm yam kab mob, uas muaj kev pheej hmoo ntawm cov kab mob atherosclerotic.
  3. Statins pab txhawb thaum ntxov rov tom qab lub plawv nres thiab cwj nrag.
  4. Cov tshuaj raug pom zoo rau cov neeg uas muaj kev tshuaj ntsuam genetic predisposition rau cov kab mob plawv.

Muaj lwm cov kev kuaj mob uas yuav tsum tau hais rau kev pab nrog statins:

Npaj-statins los ntawm lub cim tshiab ntawm cov cholesterol feem ntau yog nyob rau hauv ib qho kev zoo nkauj, tab sis lawv cov hauj lwm zoo yuav tuaj yeem tsim nyog cov nqi:

  1. Statins rov qab muaj lub zog ntawm cov hlab ntsha.
  2. Npaj normalize ntshav ncig, li no kom lub inflow ntawm cov as-ham mus rau lub plawv mob.
  3. Tom qab siv statins, qib "zoo" roj cholesterol nce.
  4. Cov tshuaj siv tiv thaiv kom tsis txhob muaj ntshav txhaws.

Cov npe ntawm cov tshuaj tshiab-cov ntsiab lus

Lub ntsiab qhov txawv ntawm cov cim ntawm lub cim dhau los yog tias lawv tau pab txhua tus, tsis muaj qhov tshwj tseg, rau cov neeg mob. Qhov tshiab tshaj plaws txhais tau hais tias ua haujlwm txawm tias thaum muaj lwm yam tshuaj lipid-lowering drugs tsis muaj zog. Tsuas yog hais tias, lawv ua haujlwm ntau dua.

Ob yam tshuaj uas niaj hnub nim no zoo tshaj plaws yog cov tshuaj Rosuvastin thiab Atorvastin, uas muaj npe rau lub ntsiab yam khoom muaj zog. Nyob hauv cov chaw muag tshuaj, muaj ntau hom tshuaj yeeb dawb.

Cov npe nrov tshaj plaws yog Rosuvastina:

Atorvastin analogs zoo li no:

Raws li kev tshawb nrhiav, Atorvastin thiab nws analogs muaj peev xwm txo qib ntawm cov cholesterol los ntawm 47%, thaum Rosuvastine nrog nws cov generics qhia tau los ntawm 55%.

Nws yog ib qho tseem ceeb kom nco ntsoov tias statins ntawm lub cim tshiab yog cov yeeb tshuaj, uas, ntawm chav kawm, muaj qee yam contraindications:

  1. Tsis txhob noj cov tshuaj lipid-lowering rau cov neeg uas muaj ib tus neeg tsis txaus ntseeg.
  2. Tsis kam statins thaum lub sijhawm xeeb menyuam thiab pub niam mis.
  3. Nrhiav lwm cov tshuaj rau cov tshuaj no yuav tsum muaj nyob hauv cov kab mob ntawm lub raum thiab cov thyroid caj pas.