Lyell's syndrome (ob lub npe hu ua Stevens-Johnson syndrome) yog ib qho kev tsis haum tshuaj loj heev, tshwm sim hauv kev sib txuas thiab kev tuag ntawm cov tawv nqaij sab nraud, thiab txoj kev qaug tshuaj ntawm tag nrho cov kab mob hauv lub cev los ntawm cov tshuaj tiv thaiv tsis tu ncua. Lyell's syndrome yog qhov thib ob uas nyuaj tshaj plaws tom qab anaphylactic shock vim hais tias tus mob uas tshwm sim los ntawm kev mob siab ntawm ib tus neeg mus rau tej yam tshuaj yeeb dej caw. Lyell's syndrome, hu ua "tshuaj lom epidermal necrolysis", thawj zaug tau piav rau xyoo 1956, tab sis txog tam sim no tsis muaj kev pom zoo hauv pawg kho mob txog qhov pib mob.
Ua rau Lyell's Syndrome
Feem ntau, Lyell's syndrome tau tshwm sim los ntawm kev ua xua.
- tom qab noj tshuaj (tshuaj tua kab mob, tshuaj sulfonamides, thiab lwm yam), kev noj tshuaj pabcuam thiab txawm tias vitamin npaj;
- nrog rau cov kab mob staphylococcal;
- raws li ib qho kev hloov ntawm qhov ua rau lub cev tsis muaj zog thaum tus kabmob ua rau tus kabmob raug mob los ntawm kev kis kabmob yav tom ntej.
Qee zaus nws tsis tuaj yeem tsim kom muaj qhov ua rau muaj kev puas tsuaj, tabsis, raws li cov kws paub txog, cov neeg muaj feem yuav muaj kev txom nyem:
- dermatitis;
- pollinoses;
- bronchial hawb pob .
Cov tsos mob ntawm Lyell's Syndrome
Tus kab mob feem ntau pib acutely nrog kub nce ntawm 40 degrees lossis ntau dua. Hauv qhov no, tus neeg mob tau mob hnyav ntawm mob taub hau thiab qhov muag mob. Ntuav thiab zawv plab yog cim tseg. Tom qab ib pliag, muaj pob khaus tshwm rau ntawm daim tawv nqaij, zoo xws li cov pob liab liab thiab liab plab, kub nyhiab los sis hnov mob. Ua ntej, qhov chaw ua kom tsis muaj teeb meem yog qhov chaw nyob hauv thaj tsam ntawm cov cheeb tsam thiab lub cheeb tsam ntawm txoj kab qij qis, ces maj mam pib nyob thoob plaws hauv lub cev.
Tus yam ntxwv ntawm Lyell's syndrome yog qhov kev tshem tawm ntawm daim tawv nqaij epidermis nrog txawm tias ib qho kev sib tshuam me me nrog daim tawv nqaij ntawm tus neeg mob. Qhov no yuav qhib los ntshav erosive formations. Nyob rau hauv cov cheeb tsam ntawm erythem, npuas tsim, uas, thaum qhib, nthuav loj loj erosive hniav nrog serous exudate. Tus kab mob kis tau yooj yim dua zaum ob uas ua rau lub cev tsis tso tawm, uas ua rau ntxhiab tsw ntxhiab hauv lub cev. Mucous daim nyias nyias ntawm lub qhov ncauj, qhov muag thiab cov qog kuj muaj kev hloov tsis zoo. Qhov txaus ntshai tshaj plaws rau kev noj qab haus huv thiab lub neej yog ua los ntawm:
- cev qhuav dej lub cev;
- mob toxicosis heev;
- siab kub cev;
- ua txhaum ntawm cov hlwv plawv;
- leukocytosis nrog tau kev loj hlob ntawm agranulocytosis thiab pancytopenia;
- ntog mus rau hauv ib qho chaw (coma).
Kev kho ntawm Lyell's Syndrome
Thaum muaj cov tsos mob ntawm tus kab mob, koj yuav tsum hu rau lub tsheb thauj neeg mob tam sim ntawd. Tus neeg mob tau muab tso rau hauv qhov kev pabcuam lossis kev pabcuam khomob tshwjxeeb. Cov xwm txheej nyob ntawm tib lub sij hawm zoo ib yam li cov neeg uas tau tsim rau cov neeg mob uas muaj kev kub ntxhov thiab cov tshuaj tua kabmob. Lub ntsiab lus tseem ceeb ntawm kev saib xyuas thiab kev kho yog mob muaj txav. Lub koom haum ntawm txoj kev kho nyob rau hauv Lyell syndrome yog li nram qab no:
- Tso tawm ntawm tag nrho cov tshuaj siv ua ntej kev txhim kho ntawm tus mob.
- Glucocorticosteroids yog cov tshuaj.
- Erosive formations raug kho nrog zaub roj thiab vitamin A.
- Saline thiab colloidal daws yog pom zoo kom rov ua kua dej los ntawm lub cev.
- Immunomodulators yog siv.
- Thaum koom nrog tus kab mob thib ob, antiseptics thiab tshuaj tua kab mob siv.
Txoj kev kho sai thiab kho kom haum sai sai sai rau kev rov qab los ntawm tus neeg mob Lyell's syndrome.