Adrainolitics yog ib pawg ntawm cov tshuaj uas cuam tshuam rau qee lub npe ntawm tus kab mob adrenergic. Nyob ntawm seb cov adrenoreceptors raug cuam tshuam los ntawm cov tshuaj no, lawv muab faib ua cov beta thiab alpha-blockers. Kev npaj raws li lawv tau teev nyob rau hauv kev sib ntaus tawm tsam ntau yam pathologies ntawm lub plawv, vascular system, nyob rau hauv cov ntaub ntawv ntawm circulatory mob thiab rau normalizing lub siab.
Npaj Alpha-Blockers
Muaj ob pawg tshuaj ntawm cov tshuaj.
Cov tsis muaj kev xaiv blockers
Cov khoom txuam kev ua haujlwm ntawm postynaptic adenoreceptors, ua rau muaj kev nthuav dav ntawm cov lumen ntawm cov hlab ntsha thiab ib qho poob rau hauv siab, nrog rau ntau tshaj tawm ntawm norepinephrine.
Tus neeg sawv cev tseem ceeb ntawm thawj pab pawg neeg yog Fentolamine, nws cov nyhuv yog ua kom cov hlab ntsha ntawm peripheral. Thaum cov khoom siv tshuaj tua kab mob, khov kho tau tiav tsis pub dhau kaum tsib nas this.
Hauv tshuaj, cov tshuaj tam sim no siv tsawg heev, tab sis nws tuaj yeem hais kom:
- bedsores lossis frostbite;
- kuaj mob ntawm pheochromocytoma;
- hypertensive ntsoog;
- hemorrhagic poob siab;
- Raynaud tus kab mob .
Lwm cov neeg sawv cev ntawm pawg neeg no:
- Pyrroxane;
- Tropafen;
- Dihydroergotamine.
Xaiv Alpha-1-adrenoblockers
Cov tshuaj yeeb dej caw yog cov dej num ntau dua thiab ntev. Lawv muaj cov nyhuv zoo ntawm cov qib roj cholesterol nyob rau hauv cov ntshav, thiab txo qhov kev pheej hmoo ntawm kev ua rau atherosclerosis. Tsis tas li ntawd, cov tshuaj yeeb dej caw tsis muaj feem xyuam rau cov txheej txheem qab zib, tsis txhob nce siab thiab sib txawv me ntsis ntawm cov kev mob tshwm sim.
Selective alpha-blockers muaj cov npe hauv qab no:
- Doxazosin;
- Ter;
- Prazon.
Los ntawm lawv cov kev ua tau zoo, cov tshuaj no nyob deb ua ntej Fentolamine. Lawv cov nyhuv loj yog los txo qhov siab los ntawm kev txo cov hluav taws xob uas ua rau cov leeg qog. Cov khoom pib tshwm sim tom qab ib teev tom qab noj tshuaj.
Cov kev qhia rau kev siv Alpha-adrenoblockers
Xav txog kev kho mob ntawm tej pawg neeg ntawm cov yeeb tshuaj:
- Nrog pathologies ntawm peripheral circulatory system (Raynaud's tus kab mob), nyob rau hauv kev kho mob ntawm qhov ntev kho qhov txhab thiab decubitus, thiab nyob rau hauv kev tswj ntawm pheochromocytomas, Fentolamine thiab Tropafen yog prescribed.
- Cov theem pib ntawm kev txhim kho ntawm prostate adenoma raug kho nrog Prozazin, uas ua rau lub qhov tawm ntawm cov zis.
- Alpha-1-adrenoblockers muaj cov kab mob siab heev. Lawv nthuav cov hlab ntsha (los ntawm qhov tsawg tshaj plaws rau cov loj tshaj), ua rau kom txo tau qhov siab. Kev txo qis dua ua rau muaj teeb meem loj hauv qhov ntsaws kabmob ntawm lub myocardium, uas ua rau cov tshuaj no ua rau hauv kuv lub cev ua pauj .
- Kev siv mus sij hawm ntev, Prazonin thiab Doxazine yog siv.
- Fostopolitic cov khoom yog cog nrog Fentolamin thiab Prazonin.
- Diabergergotamine yog siv rau cov qog nqaij hlav, nrog rau cov ntaub ntawv mob plawv thiab cov hlab ntsha hauv plab.
Contraindications Alpha-blockers
Txhob muab tshuaj rau cov neeg uas muaj cov kev tsis sib haum nram qab no:
- bradycardia;
- mob loj heev atherosclerosis;
- plawv palpitations;
- nrog lub raum kab mob;
- propensity to orthostatic cov tshuaj tiv thaiv, yam ntxwv rau cov neeg laus uas muaj ntshav qab zib;
- ischemic disease tsis paralel tswj ntawm beta-blockers;
- pathology ntawm cerebral ncig.
Txheeb tus kwv tij yog qhov uas cev xeeb tub.
Undesirable teebmeem yog tshwm sim li:
- ntev li ntawm siab poob;
- qhov pib ntawm o;
- mob taub hau;
- lub plawv dhia ceev faj;
- tachycardia;
- vasodilation;
- o ntawm cov hnyuv membrane;
- xeev siab;
- insomnia;
- mob hauv cov leeg.