Glycated hemoglobin yog ib qho ntawm cov kab mob biochemical uas qhia qhov nruab nrab theem ntawm qab zib hauv cov ntshav rau lub sijhawm ntev. Kev soj ntsuam rau glycated hemoglobin plays lub luag hauj lwm tseem ceeb hauv kev mob ntawm cov ntshav qab zib mellitus, thiab ntxiv hauv kev soj ntsuam ntawm cov mob ntawm cov neeg mob uas muaj tus kab mob no.
Dab tsi yog qhov kev ntsuam xyuas qhia rau glycated hemoglobin?
Glycated hemoglobin yog nyob hauv cov ntshav ntawm txhua tus neeg, thiab nws tus nqi yog txiav txim tias yog feem pua ntawm cov ntshav tag nrho cov ntshav.
Glycated hemoglobin yog tsim los ntawm fusion ntawm qabzib thiab hemoglobin, uas cov enzymes tsis koom. Yog li ntawd, muaj ib qho mob uas tsis zoo thiab tsis tuaj yeem tshwm sim hauv cov ntshav liab (erythrocytes) rau tag nrho lawv lub neej. Vim tias hemoglobin nrog rau cov ntshav qab zib tsis tau sai li sai tau, thiab lub neej ntawm cov qe ntshav liab tuaj yeem tau ntev txog 120 hnub, qhov kev ntsuas no txhais tsis txog theem ntawm cov ntshav qab zib, tab sis kwv yees li ntawm 3 lub hlis.
Txhawb thiab txo qis tau hemoglobin
Rau kev tshawb nrhiav pom, qhov kev ntsuam xyuas no yog siv rau ntshav qab zib mellitus ntawm txhua hom thiab cov mob ua ntej cov ntshav qab zib. Qhov siab dua ntawm cov suab thaj, qhov ntau dua hemoglobin yog khi, thiab yog li ntawd glycated hemoglobin yog siab rau cov neeg mob ntshav qab zib mellitus.
Tus qauv yog xam los ntawm 4 mus rau 6%, nrog glycated hemoglobin los ntawm 6.5 mus 7.5% nws yog ib yam mob uas muaj ntshav qab zib, qhov tseem ceeb tshaj qhia tau hais tias muaj cov kab mob ntshav qab zib tsis muaj zog. Tsis tas li, iron deficiency tuaj yeem yog qhov ua rau.
Txawm li cas los xij, muaj ntau cov kab mob pathological, vim tias cov tshuaj glycated hemoglobin tuaj yeem nce lossis tsawg dua, thiab daim duab kos yog distorted.
Qhov ntsuas yuav raug nce nrog:
- hlau deficiency (qhov no, qhov tsis muaj hlau deficiency anemia, tag nrho cov ntshav ntsuas phaus ntshav, thiab vim li no tus txheeb ze txheeb ze dua);
- lom cov kua qaub lossis dej cawv;
- raum tsis ua hauj lwm vim qhov txuam rau hauv cov ntshav ntawm cov khoom lwj, uas tsis tawm hauv lub cev;
- tej thaj chaw deb.
Txo glycated hemoglobin tuaj yeem tshwm sim thaum:
- los ntshav;
- lub caij nyoog pliance hypoglycemia;
- hemolytic anemia (nyob rau hauv uas lub neej ntawm kev qis ntshav liab qis);
- tom qab cov ntshav txhab.
Kev ntsuam xyuas ntshav rau glycated hemoglobin
Tsis zoo li feem ntau cov kev xeem, tso ntshav rau glycated hemoglobin tsis tuaj yeem ua rau ntawm lub plab tas. Vim tias qhov kev tshawb fawb no qhia tau hais tias qhov nruab nrab qab zib tshaj li ntawm peb lub hlis, cov cim ntsuas tam sim no rau nws tuaj yeem tsis cuam tshuam rau.
Tsis tas li, cov qib glycated hemoglobin tsis cuam tshuam los yog cuam tshuam los ntawm qhov tsis tshua muaj tsawg ntawm cov tshuaj, mob khaub thuas thiab kab mob ntsws, lub siab lub xeev ntawm tus neeg mob. Cov kev qhia yuav raug cuam tshuam los ntawm cov ntshav poob (muab cov kev qoj ib ce ntawm kev coj khaub ncaws nrog poj niam los ntshav heev) thiab qee qhov
Tsis tas li, distort cov indicators (ib nyuag txo lawv) yuav siv sij hawm li ob peb hnub ua ntej qhov kev ntsuam xyuas iron hlau, siv ntau cov khoom noj uas muaj iron-iron thiab liab caw. Yog tias cov tshuaj yuav ua rau tag nrho cov kev hemoglobin yuav tsum noj txhua zaus, ces lawv tsis thim qhov duab saib mob.
Nws yuav tsum tau nyob rau hauv lub hlwb hais tias kev tshawb fawb ntawm glycated hemoglobin nyob rau hauv ntau lub chaw (siv ntau txoj kev) yuav qhia tau sib txawv. Yog li, yog tias qhov kev ntsuam xyuas tau ua tiav tsis tu ncua, los soj ntsuam qhov kev mob, nws yog qhov zoo tshaj rau kev siv cov kev pab ntawm ib lub chaw kuaj mob.