Follicle-stimulating hormone (FSH) yog ib yam tshuaj hormone uas tsim los ntawm lub tshuab hypothalamic-pituitary, ntau precisely - hauv pituitary. Cov kev cai ntawm nws cov khoom siv yog kwv yees los ntawm hypothalamus, thiab cov concentration ntawm FSH ncaj qha nyob ntawm theem ntawm kev sib deev hormones nyob rau hauv cov ntshav.
Nrog me ntsis txo hauv lawv cov concentration, stimulation ntawm FSH tsim tshwm sim, thiab ntawm qib siab - synthesis ntawm follicle-stimulating hormone decreases. Kuj tseem ceeb rau cov synthesis ntawm FSH inhibin-B, uas yog nyob rau hauv lub hlwb ntawm lub zes qe menyuam thiab nyob rau hauv cov tubular tubules ntawm cov txiv neej.
Ntaus ntau lawm
Tus synthesis ntawm FSH tsis yog ib qho tas li, tab sis ib tug ua cim pulsating. Yog li, thaum cov tshuaj synthesized follicle-stimulating hormone yog cais rau hauv cov poj niam ntshav, nws cov concentration nce hnyav thiab tshaj qhov tsim nyog norm ntawm 2, thiab txawm 2.5 zaug. Tom qab ntawd theem qis txo. Qhov siab tshaj plaws yog qhov pom nyob rau hauv qib theem ntawm kev coj khaub ncaws.
FSH qib hauv ntau lub sijhawm ntawm tus poj niam lub neej
Cov ntsiab lus ntawm cov tshuaj hormone hauv stimulating hauv cov ntshav ntawm cov poj niam tsis muaj qhov nqi tas li thiab feem ntau li ntawm cov kev txwv ntawm 1.7-135 IU / l.
Yog li cov ntsiab lus ntawm no hormone nyob rau hauv cov poj niam cov ntshav nws nyob ntawm cov theem (theem) ntawm kev coj khaub ncaws. Hauv qib qis , FSH yog feem ntau 3.49-13 IU / L, nyob rau hauv luteal nws txo - 1.69-7.7. Qhov loj tshaj concentration ntawm lub hormone ncav lub sij hawm ntawm ovulation - 4.69-22 IU / l. Thaum lub sijhawm cev xeeb tub, qhov concentration ntawm FSH txo tsawg zuj zus, thiab nce mus txog 0.01-0.3 IU / L.
Thaum lub sij hawm postmenopausal, cov ntsiab lus ntawm FSH nce, uas yog vim inhibition ntawm cov synthesis ntawm estradiol thiab progesterone. Nyob rau lub sij hawm no, cov concentration ntawm FSH nce mus txog 26-135 IU / l.
Lub ntsiab lus ntawm cov tshuaj hormone stimulating hormone yog qis dua tus qauv, ua rau txoj kev loj hlob ntawm:
- Callman Syndrome;
- tsis muaj cov khoom tsim los ntawm lub caj pas pituitary;
- qog ntawm ovaries, noob qes.
Nyeg, nce qhov concentration of follicle-stimulating hormone saum tus qauv, yuav ua tau kom cov kab mob xws li:
- kab mob ntawm cov gonads;
- pituitary qog;
- lub hlwv ntawm zes qe menyuam;
- underdevelopment ntawm gonads;
- ntxov ntxov puberty.
Lub ntsiab lus
FSH, ua ke nyob rau hauv cov poj niam lub cev, txhawb nqa qhov maturation ntawm follicles thiab saib xyuas lawv cov kev npaj rau cov txheej txheem ntawm ovulation. Qhov no hormone ncaj qha tswj thawj theem ntawm tag nrho cov kev coj khaub ncaws, lub voj voog follicular. Nyob rau hauv nws lub hwj, lub follicle ho nce nyob rau hauv qhov loj thiab pib tsim estradiol . Ntawm qhov kawg ntawm theem follicular, qhov concentration ntawm FSH yuav ua rau kom muaj zog. Ces lub follicle bursts, thiab los ntawm nws ib tug paub tab qe tawm lub peritoneal kab noj hniav, uas yog, tus txheej txheem ntawm ovulation yuav siv qhov chaw.
Thaum lub sij hawm thib 2 ntawm lub voj voog, luteal, FSH txhawb nqa cov khoom siv ncaj qha ntawm progesterone. Thaum ib tug poj niam yau muaj hnub nyoog 45-50 xyoos, tus mob menopause tshwm sim, uas estradiol thiab progesterone tsis ua los ntawm ovaries, uas ua rau qhov nce hauv concentration hauv FSH lub cev.
FSH muaj nyob rau hauv cov txiv neej, tab sis nyob rau ntawm ib qhov chaw qis dua. Cov tshuaj hormone no pib lub txheej txheem ntawm cov tshuaj tua kab mob hauv cov txiv neej hluas. Nws yog FSH uas pab txhawb rau kev loj hlob ntawm cov txiv neej seminiferous tubules thiab nce qib ntawm cov tshuaj testosterone.
Lub siab FSH siab tau pom thaum me nyuam mos yug. Thaum cov tub hluas nws txo qis rau ib nrab xyoo, thiab thaum cov ntxhais - ncav cuag tus qauv lossis tus nqi rau 1-1,5 xyoos. Lub sij hawm tom qab nws cov ntsiab lus tsub ntxiv thaum mus txog qhov kev hloov lub hnub nyoog, thaum FSH tswj hwm tus txheej txheem ntawm kev puberty.