Ib qho ntawm feem ntau yog ua rau infertility yog hyperandrogenism nyob rau hauv cov poj niam - lub pathology ntawm endocrine system. Qhov kev ntsuam xyuas no yog kuaj tshaj li ntawm 20% ntawm cov poj niam.
Hyperandrogenism nyob rau hauv cov poj niam - ua rau
Hyperandrogenia rau cov poj niam yog ib qho txiaj ntsim ntawm cov kab mob endocrine, nrog rau cov hlav hauv qhov kawg ntawm qhov kev ua rau endocrine - pituitary (raws li ib feem ntawm qhov kev kho hypothalamic-pituitary), thymus, thyroid, pancreas, adrenals thiab gonads). Tsis tas li ntawd, qhov ua rau muaj ntau tus txiv neej hormones - androgens - yog adrenogenital syndrome. Ntau tus txiv neej cov tshuaj hormones yog hloov mus rau hauv glucocorticoids hauv qhov kev txiav txim ntawm tus tshwj xeeb enzyme, cov khoom uas tau tshwm sim ntawm lub programmed genetically. Lwm qhov laj thawj rau kev hyperandrogenism hauv cov poj niam hu ua adrenal hlav. Qhov nce hauv hlwb uas tsim androgens kuj nce tus naj npawb ntawm cov txiv neej cov tshuaj hormones. Ua kom cov txiv neej cov roj ntsha ntau ntxiv tuaj yeem tuaj yeem los ntawm qhov ua rau ntawm daim tawv nqaij los ntawm cov txiv neej pw ua ke - testosterone.
Hyperandrogenia rau cov poj niam - cov tsos mob
Hyperandrogenia yog ib qhov mob uas yog clinically pom los ntawm pob txuv, seborrhea, thiab hirsutismome androgen dependent alopecia. Hauv cov ntaub ntawv no, cov kev kuaj ntshav muaj peev xwm qhia tau kom siab lossis nyob rau theem qis ntawm androgens (txiv neej cov tshuaj hormones). Cov kev hloov ntawm txoj kev zes qe menyuam, tus cwj pwm ntawm cov qe menyuam polycystic, kuj kuaj tau. Lub ntsiab feature, tseem yam ntxwv ntawm lub syndrome ntawm hyperandrogenism nyob rau hauv cov poj niam, tshwm sim los ntawm kev nce hauv androgens, yog ib tug ua txhaum ntawm kev coj khaub ncaws, tom qab infertility, anovulatory mus. Hyperandrogenia nyob rau hauv cov ntxhais qeeb rau qhov pib ntawm menstruation rau ob peb xyoo.
Hyperandrogenism nyob rau hauv cov poj niam yog nrog los ntawm kev rog. Kev hloov ntawm daim tawv nqaij yog nrog los ntawm kev tsim ntawm pob txuv (blackheads). Tsis tas li ntawd, hyperandrogenia ua rau muaj kev hloov ntawm kev hloov uas ua rau tsim muaj cov hlwv me me thiab tsim muaj cov tshuaj ntsaws nyob ib ncig ntawm lub zes qe menyuam. Ntawm cov cim sab nraud ntawm qib qis ntawm androgens, pob txuv eruptions, ntau txoj kev loj hlob ntawm plaub hau ntawm ob txhais ceg, ob txhais tes. Cov kev hloov loj heev hauv zes qe menyuam tuaj yeem ua rau lub cev tsis tau ntawm cov qe, polycystosis.
Hyperandrogenism thiab cev xeeb tub
Cov kws kho tshwj xeeb qhia txog kev hyperandrogenism ntawm adrenal, yug menyuam thiab qoob loo. Hyperandrogenia ntawm poj niam ntawm genus yog tshwm sim los ntawm cov ntsiab lus ntawm cov txiv neej poj niam pw ua ke - testosterone, uas yog ua los ntawm kev zes qe menyuam. Qhov ua rau ntawm no mob yog ntau yam kab mob ntawm ovaries: qog, polycystosis. Nws kuj yog feem ntau kuaj pom cov menyuam ntxhais uas koom nrog cov kev ua si fais fab. Thaum cev xeeb tub, hyperandrogenia ntawm cov poj niam ntawm genus tsis ua rau kev hem thawj rau hauv lub plab thiab tus me nyuam, los yog nws puas yuav tsum tau kho. Adrenal hyperandrogenism, feem ntau yog ib qho kev xeeb menyuam los yog ua los ntawm qhov tsis muaj ntau lub enzymes uas koom hauv tsim cortisol, yog ib qho txaus ntshai rau cov neeg uas npaj muaj cev xeeb tub los yog xeeb tub.
Hyperandrogenia rau cov poj niam thaum cev xeeb tub yuav ua rau muaj kev phom sij heev dua qub thaum yug me nyuam, xws li tsis tuaj yeem tawm ntawm amniotic kua thiab tsis muaj zog ua haujlwm.