Tus kab mob Neurodegenerative, thawj zaug tau piav thiab kawm hauv kev nthuav dav los ntawm German psychiatrist A. Alzheimer nyob rau hauv lub xyoo pua 20th, yog ib hom kev dementia (dementia), uas yog ntau tus poj niam ib nrab ntawm cov pejxeem nyob rau cov laus laus. Feem ntau, Alzheimer's tus kab mob nyob hauv cov neeg hluas.
Alzheimer's kab mob - qhov ua rau ntawm
Senile dementia ntawm tus Alzheimer 's hom, raws li lawv tseem hu cov pathology nyob rau hauv kev saib xyuas, tsim raws li mechanisms tseem tsis tau clarified. Qhov feem ntau txhim khu kev ntseeg ntawm keeb kwm ntawm tus kab mob, raws li feem ntau cov kws txawj, yog lub amyloid hypothesis. Raws li nws, Alzheimer 's ua rau Alzheimer' s kab mob yog txuam nrog deposition hauv lub paj hlwb ntawm beta-amyloid - ib fragment ntawm cov protein uas ua kev tiv thaiv thiab trophic functions hauv lub cev. Vim li ntawd, cov plhaub taum plab thiab cov pob tangles tsim tsis tsim, uas ua rau kom muaj kev tuag ntawm lub hlwb.
Cov kws tshawb fawb ntseeg tias Alzheimer's disease yog ib hom kab mob multifactorial, nyob rau hauv txoj kev loj hlob ntawm cov kev tsis sib xws uas tsis muaj kev cuam tshuam. Tsis ntev los no cov kev tshawb fawb tau qhia peb noob, cov deviations ntawm uas muaj peev xwm ntawm provoking tus kab mob. Tsis tas li ntawd, muaj ntau lub hauv paus uas ua rau muaj qhov sib txawv ntawm qhov pib ntawm kev mob ntsws. Cov no suav nrog:
- mob raug mob craniocerebral ;
- muaj kev puas siab ntsws loj heev;
- tsis muaj kev puas hlwb;
- ntshav siab;
- atherosclerotic cov kev hloov hauv cov hlab ntsha ;
- oxygen deficiency;
- tsis muaj kev sib haum xeeb;
- rog dhau;
- ntau tau piam thaj;
- cawv miskas;
- haus luam yeeb.
Alzheimer's disease - cov tsos mob thiab cov cim qhia
Tus kab mob no maj mam nce, thiab thaum lub sij hawm siv thiab tus naj npawb ntawm nws cov tshwm sim yog nce. Cov cim xub pib feem ntau tshwm sim rau cov hnub nyoog ib txwm tshwm sim, qhov teeb meem ntawm kev ntxhov siab, qaug zog, thiab yog li ntawd ntau tus neeg tsis quav ntsej. Tsis tas li ntawd, Alzheimer's cov tsos mob tshwm sim ntau dua, cuam tshuam lub neej txhua hnub tsis yog ntawm cov neeg mob lawv tus kheej, tab sis kuj ntawm cov neeg nyob ib ncig ntawm lawv.
Alzheimer's disease - hnub nyoog
Cov txiaj ntsim taw qhia ntawm Alzheimer tus kab mob feem ntau ua rau pom muaj hnub nyoog 65 xyoos, tab sis thawj tus kab mob sib txawv hauv cov qauv ntawm lub hlwb tshwm sim 10-15 xyoo ua ntej. Nyuam qhuav muaj qhov kev xav ntawm "rejuvenation" ntawm pathology, uas tau kuaj pom tias muaj hnub nyoog 45 xyoo. Thaum muaj kev tshuaj ntsuam genetic abnormalities, Alzheimer's tus kabmob tuaj yeem tsim muaj hnub nyoog yau dua, uas yog los ntawm ib daim duab zoo tib yam.
Cov theem ntawm Alzheimer's Disease
Alzheimer's senile dementia, cov tsos mob ntawm cov kev vam meej nrog lub sij hawm, muab cais ua raws li qhov phem ntawm kev mob hauv plaub theem. Cia peb xav txog lawv nyob hauv ntau yam:
1. Tus thawj theem yog qhov mob ua ntej, qhia txog cov nram no:
- ib qho kev nco tsis meej xeeb nrog lub cim xeeb tsis ntev los ntawm cov txheej xwm tsis ntev los no thiab cov ntaub ntawv tshiab nrog kev txuag ntawm lub sijhawm ntev;
- ua txhaum ntawm semantic nco (nyob rau ntawm lub ntsiab lus ntawm cov lus, lawv kev sib cais, thiab lwm yam);
- tsis pom zoo;
- apathy;
- tsis sib haum xeeb;
- teeb meem nrog kev npaj ua ub no;
- muaj teeb meem nrog kev xav thiab kev xav paub tseeb;
- tsis muaj kev txaus siab hauv lawv txoj kev nyiam, kev txias ntawm kev sib raug zoo nrog kev sib raug zoo.
2. Qhov thib ob theem yog thaum ntxov dementia, uas cov kev hloov hauv tus neeg mob tus cwj pwm zoo dua rau lwm tus. Cov cim nram qab no raug cim tseg:
- hnyav zog teeb meem;
- ua txhaum ntawm ntau hom kev xaav;
- txo cov lus;
- txo qis rau kev ceev ntawm kev hais lus;
- ua txhaum cai ntawm kev tsav tsheb.
3. Qhov thib peb yog theem ntawm dementia qib, uas yog lub hauv paus ntawm qhov kev paub ntawm qhov tsis zoo thiab qhov tshwm sim ntawm lwm cov kev mob ntsws pathological:
- Tsis muaj qab hau, tsis tseem ceeb, hais lus ntawm cov lus;
- tsis txawj nyeem ntawv thiab sau ntawv;
- ib qho kev xiam oob khab loj heev, thaum tus neeg mob tsis paub cov txheeb ze ze, lub sij hawm ntev yuav tawg;
- lub sijhawm uas tshwm sim ntawm kev mob hlwb;
- txob taus;
- tearfulness;
- kev mob ntawm kev mob plawv;
- pw tsaug zog mob;
- urinary tuskheej.
4. Lub xeem dhau - Alzheimer's tus kabmob - ua rau cov neeg mob tsis tuaj yeem sab nraud ntawm kev pab sab nraud yuav luag tag nrho cov kev txawj ntawm qhov kev pab cuam yus tus kheej tau ploj lawm. Cov duab kos nrog:
- tsis tau hais lus;
- tsis tu ncua;
- lub cev qaug;
- nyuaj mus txog thaum ua tiav kev tsis tuaj yeem.
Alzheimer's disease - lub neej expectancy
Nyob rau theem no hauv kev txhim kho ntawm kev tshawb fawb, tus kab mob yog txiav txim siab tsis tau. Thaum ib tus neeg los ntawm cov neeg uas nws hlub raug cuam tshuam los ntawm Alzheimer's disease, theem kawg, ntau npaum li cas nrog nws, excites ntau tus neeg. Nws yog ib qho tseem ceeb kom to taub tias thaum muaj kev dementia mob lub neej ntawm cov neeg mob tau txiav txim siab los ntawm kev saib xyuas zoo rau lawv. Feem ntau, thaum lub sij hawm kawg ntawm tus kab mob yog pom, nyob tsis muaj tshaj ib xyoos, nrog kev kho mob zoo - ntau dua. Hauv qhov no, kev tuag tsis tshwm sim vim Alzheimer's tus kab mob nws tus kheej, tab sis vim muaj teeb meem ntsig txog immobilisation - mob ntsws, qhov siab, thrombosis, thiab lwm yam.
Alzheimer's kab mob - kev kho mob
Yog hais tias nyob rau hauv lub hnub nyoog laus kom paub txog tus kab mob rau ib tus kws kho mob tshwj xeeb yog qhov yooj yim rau txoj kev tshawb no ntawm anamnesis thiab cov kev kuaj pom ntawm cov cwj pwm hlwb thiab keeb hlav neuropsychological, thaum ntxov Alzheimer's tus kab mob lawm ntau dua. Rau kev kuaj mob kom zoo, cov kev ntsuam xyuas tshwj xeeb txog paj hlwb thiab cov kev tshawb fawb muaj cai:
- khoos phis tawj thiab sib nqus resonance imaging ;
- single-photon emission computed tomography;
- positron emission tomography.
Txij li thaum nws tseem tsis tau los kho kho pathology, txoj kev kho yog tswj kev ua txhua yam kev kawm, qeeb qeeb ntawm kev vam meej thiab kev txhim kho tus neeg mob lub neej zoo, cov kev xav ntawm kev xav hauv psychosocial ua si tseem ceeb. Cov yav tas muaj xws li:
- suab paj nruag kho mob - cov neeg mob muaj suab paj nruag uas qhia txog kev xav zoo, koom haum nrog lub sijhawm thaum yau thiab kev hluas;
- kos duab kho - kawm hauv cov duab yooj yooj yim (daim duab, qauv);
- kev xav nrog - cuam tshuam nrog tus neeg mob hauv cov haujlwm tsis ua haujlwm, ua kom lub cev ua ub ua no;
- kev txhawb rau kev txawj ntse - daws teeb meem kev sib tw, nyeem ntawv, cim cov lus thiab cov nqe lus, thiab lwm yam.
Thaum tu tus neeg mob yuav tsum ua raws li cov lus qhia nram qab no:
- ceev faj thiab ua siab ntev;
- muab sijhawm ntawm tag nrho cov haujlwm tseem ceeb;
- kev tsim cov kev xav tau ntawm kev nyob;
- ua raws li kev niaj hnub ua;
- kev tiv thaiv ntawm cov teeb meem.
Alzheimer's tus kab mob - kev kho mob (tshuaj)
Cov neeg mob hu ua Alzheimer's disease yuav tau txais cov tshuaj nram no rau kev kho mob:
- cholinesterase inhibitors (Razadin, Aricept, Exelon) - cuam tshuam nrog lub cleavage ntawm neurotransmitter acetylcholine;
- ib nrab antagonists ntawm glutamate (Memantine) - txo qhov theem ntawm lub ntsiab stimulating kho lub hlwb, ua kev puas tsuaj rau paj hlwb;
- Neuroleptics (Aminazine, Haloperidol, Clozapine) - kom tshem tawm cov kws kho mob hlwb thiab cov paj hlwb;
- tranquilizers (Imovan, Buspirone) - tshem tawm kev ntxhov siab, txo siab ntsws xav;
- antidepressants (Prozac, Anafanil, Sertralin) - nres nres ntawm aggression, ntshai nres.
Kev kho mob ntawm Alzheimer's tus kab mob pej xeem tshuaj
Alzheimer's disease, kev kho mob hauv tsev uas yog ua tiav raws li cov txheej txheem uas kws kho los ntawm kws kho mob, tsis cais kev siv pej xeem cov tswv yim los pab txhawb txoj kev khiav. Yog li, ntau tus neeg mob tuaj yeem pom zoo cov nyiaj uas zoo rau cov ntshav khiav, kev noj zaubmov ntawm lub hlwb, nce lub suab ntawm lub cev:
- tincture ntawm ginseng paus;
- tincture ntawm aralia;
- tincture ntawm lub Dioscorean ntawm Caucasus, lwm yam zoo li
Tshiab nyob rau hauv kev kho ntawm Alzheimer tus kab mob
Kev kho mob ntawm Alzheimer tus kab mob thaum ntxov yog tus yuam sij rau kev siv zog sai sai thiab ua rau lub neej ntawm tus neeg mob. Cov kws tshawb fawb tseem mus tshawb nrhiav cov kev kho mob zoo, thiab ib qho ntawm lub foremost ntawm lub sij hawm no tuaj yeem raug hu ua:
- implantation ntawm qia hlwb;
- cov kev taw qhia txog nanoparticles uas khi thiab txov proteinaceous plaques;
- siv cov tshuaj tiv thaiv kab mob uas tiv thaiv kev tiv thaiv tawm tsam amyloid peptides.
Kev Tiv Thaiv ntawm Alzheimer's Disease
Nws tsis muaj cov hau kev uas yuav tiv thaiv tau Alzheimer's rau cov poj niam, tab sis kev ua raws li kev noj qab nyob zoo yuav txo tau txoj kev pheej hmoo ntawm tus kab mob no. Lub tswv yim tseem ceeb yog raws li nram no:
- kev noj zaub mov;
- kev qoj ib ce;
- tsis kam haus dej cawv thiab haus luam yeeb;
- kev paub txog kev txawj ntse;
- tswj cov ntshav siab thiab lub cev qhov hnyav.
Kuaj rau Alzheimer's Disease
Muaj ntau qhov kev ntsuam xyuas kev ntsuas tau raug tsim, ua tsaug rau cov txheej txheem koj lub cev muaj peev xwm tshwm sim nyob rau theem pib. Ntau yam ntawm lawv tuaj yeem nqa hauv tsev. Piv txwv, koj tuaj yeem hais kom ib tug neeg kos tus cim rau ntawm daim ntawv nrog tus xauv moos uas nws txhais tes qhia lub sijhawm. Ntawm qhov teeb meem hauv kev ua haujlwm ntawm lub hlwb hais tias kev tsis tau ntawm qhov ua tau zoo ntawm txoj hauj lwm no, qhov kev xav ntawm kev ua yuam kev (disconnection ntawm tus hu thiab cov zauv, cov teeb meem ntawm qhov chaw ntawm cov xib xub, thiab lwm yam). Xyuas koj cov neeg uas koj hlub rau lub caij ua ntej rau tus kab mob, muab lawv ob peb yam yooj yim.
Cov naj npawb ntawm tus naj npawb 1 (txheeb xyuas cov cim xeeb thiab cim tsis nco qab):
- Tom qab ib feeb, sau lub npe kaum pib nrog tsab ntawv "A" lossis "B".
- Tom qab ib feeb, hu kaum tsiaj.
- Nyeem cov ntawv encrypted:
94NN03 S006H3NN3 P0K4ZY8437, К4KN3 U9N8N73LЬNЫ3 83HN M0Ж37 93Л47Ь Н4Ш Р4ЗУМ!
8P3Ch 47LYYN3 83HN!
CH4H4L4 E70 6ND0 7RU9H0, H0 S3YCH4S H4 E70Y S7R0K3 84H P4ZUM CHN7437 E70 4870M47NCH3SCN, H3 Z49UMY84YA 06 E70M. T0P9NCb.
Cov naj npawb 2 (xyuas cov haujlwm ntawm cov hlab ntsha paj nruag):
- Npaj ib lub thauv ntawm cov txiv laum huab xeeb (nws cov kua txiv paub zoo rau txhua tus) thiab tus kav.
- Cov ntawv yuav tsum kaw nws lub qhov muag thiab lub qhov ncauj.
- Nqa roj mus rau nws sab laug nostril ntawm ib tug deb ntawm 23 cm.
- Kev hno, qhov kev sim yuav tsum tau txiav txim siab qhov khoom.