Ampicillin yog ib yam tshuaj tua kab mob ntsws (bactericidal antibacterial antibiotic) ntawm ntau hom tshuaj penicillins. Qhov kev txiav txim ntawm cov khoom nyhuv ntawm cov tshuaj yog qhia rau kev puas tsuaj ntawm membrane ntawm microbial hlwb, thiab cov txheej txheem ntawm cov txheej txheem metabolic, uas yog, cov synthesis ntawm cov kab mob ntawm cov kab mob hauv cov kab mob, uas tiv thaiv lawv los ntawm kev sib txuam thiab rhuav tseg lub hlwb lawv tus kheej. Cov nyhuv ntawm Ampicillin yog qhov kev puas tsuaj rau Gram-positive, Gram-negative bacteria, thiab rau cov kab mob hauv plab hnyuv.
Cov tshuaj yog acid-sai. Cov cuab yeej no tsis tso cai rau cov kua txiv peej kua qaub los cuam tshuam rau cov tshuaj thaum noj mis, qhov nqus tsuas yog 40% xwb. Txaus siab tsis tshwm sim, cov tshuaj siv khiav tawm tsis muaj biotransformation. Ampicillin yuav pab tau thaum muaj lwm yam tshuaj tua kab mob uas tiv thaiv tsis tau tus kab mob.
Cov kev qhia siv Ampicillin
Txij li thaum Ampicillin muaj ntau qhov kev txiav txim, rhuav tshem ntau hom kab mob, nws yog siv los kho cov kab mob hauv ntau lub cev.
1. Rau cov kab mob ntawm txoj hlab ua pa thiab ENT kabmob Ampicillin yog tus kws kho rau cov kev mob xws li:
- pharyngitis;
- tonsillitis;
- sinusitis;
- angina;
- liab plab liab;
- laryngitis;
- bronchitis;
- abscess ntawm lub ntsws;
- mob ntsws o;
- bronchopneumonia;
- pleurisy;
- otitis media.
2. Nrog rau kab mob ntawm lub cev genitourinary thiab kab mob hauv lub raum, qhov tshuaj tua kab mob no pab nrog cov kab mob nram qab no los ntawm enterococcus, proteus, E. coli los yog mixed kab:
- pielit;
- pyelonephritis;
- mob caj pas;
- cystitis;
- gonorrhea;
- mob khees xaws.
3. Rau cov kab mob ntawm cov kabmob kua kabmob (biliary) Ampicillin yog qhia rau:
- cholecystitis;
- cholangitis.
4. Ampicillin yog tshuaj rau cov poj niam cev xeeb tub thaum raug tus kab mob chlamydial, yog tias muaj kev tsis zoo rau Erythromycin.
5. Rau cov kab mob sib kis ntawm cov nqaij mos thiab tawv, xws li:
- impetigo;
- lub ntsej muag;
- dermatosis theem nrab ntawm tus kab mob;
- purulent wounds.
6. Nyob rau hauv cov kab mob ntawm cov kab mob musculoskeletal, uas yog cov kab mob xws li:
- rheumatism;
- mob caj dab;
- osteomyelitis ;
- listeriosis;
- pasteurellosis.
7. Thaum txoj hnyuv hla cov kab mob xws li:
- salmonellosis;
- salmonella;
- dysentery;
- typhoid fever;
- paratyphus;
- peritonitis.
Tsis tas li ntawd, Ampicillin yog tus kws kho mob rau cov kab mob loj xws li mob meningitis, endocarditis, sepsis (septicemia los yog blood infections), odontogenic infections ntawm lub qhov ncauj kab noj hniav.
Ampicillin nyob rau hauv kev kho mob ntawm lub caj pas qa
Tus mob Angina yog ib qho kab mob rau cov kab mob uas tshwm sim los ntawm tus kab mob hu ua streptococcal. Txoj kev zoo tshaj plaws ntawm txoj kev kho mob ntawm tus mob streptococcal yog kho nrog tshuaj tua kab mob ntawm penicillin series, hauv particular, Ampicillin rau 10-14 hnub.
Hauv qhov no, txoj kev loj hlob ntawm tus kab mob yog thawj zaug inhibited, vim txoj kev faib thiab kev loj hlob ntawm cov kab mob yog blocked, thiab ces tus kab mob sai tuag tawm los ntawm kev puas tsuaj mus tas li ntawm phab ntsa, tsis muaj peev xwm rov qab los thiab lawv qhov kawg tuag ntawm cov kab mob pathogenic. Kev xyaum ua pom tau hais tias lub sij hawm nyob rau hnub thib ob ntawm kev noj tshuaj, thiab tom qab 4-5 hnub cov tsos mob yuav ploj mus. Hauv kev kho mob ntawm tus mob streptococcal angina, koob tshuaj Ampicillin rau cov neeg laus ranges ntawm 0.25 mus 0.5 grams. Siv cov tshuaj 4 zaug ib hnub twg.
Kev kho mob ntsws nrog cov ampicillin
Mob ntsws (Pneumonia) paub tias yog kab mob kis tau los ntawm cov kab mob pathogenic. Nws yog ib qhov tsim nyog yuav tau kho cov kab mob ntsws kom pom tau, tab sis lub ntsiab lus tseem ceeb ntawm "yeej" tshaj qhov mob yog cov tshuaj tua kab mob. Ampicillin kev lis haujlwm nrog txoj haujlwm no zoo, qhov no yog vim li cas feem ntau cov kws kho mob muab nws sau. Txawm tias zoo dua, yog tias koj siv Ampicillin-sulbactam, vim nws muaj ntau ntxiv ntawm qhov kev txiav txim thiab raug rhuav tshem cov kab mob cov kab mob uas tiv taus Ampicillin. Raws li txoj cai, nrog rau kev mob ntsws (pneumonia), ib qho tshuaj tua kab mob yuav tsum tau txhaj rau cov kab mob mus rau hauv cov ntshav tawm sai.