Nonsteroidal anti-inflammatory drugs (NSAIDs) yog ib pawg tshuaj muaj txiaj ntsig zoo uas muaj cov tshuaj tua kab mob hauv qab no, cov tshuaj tiv thaiv thiab mob nyhav.
Yog li, cov tshuaj no pab txo kev mob, kub cev thiab mob. Lawv qhov kev txiav txim yog raws li qhov kev txwv ntawm cov enzymes, uas yog cov synthesis ntawm cov tshuaj uas catalyze inflammatory txheej txheem tshwm sim nyob rau hauv lub cev. Hauv kev sib piv rau cov kab mob glucocorticoids (cov tshuaj hormonal), cov nyhuv uas zoo sib xws, cov tshuaj tsis yog mob steroid tsis muaj xws li muaj neeg coob heev ntawm cov khoom tsis zoo.
Tsis tas li ntawd, qee cov NSAIDs muaj cov nyhuv los tiv thaiv cov kab mob (dilution, kev txhim kho cov ntshav fluidity), thiab cov tshuaj tua kabmob (immunosuppressive effect).
Cov kev qhia rau kev siv cov NSAIDs
Feem ntau, cov tshuaj tua tsis tau-cov tshuaj tiv thaiv yog siv cov kab mob mob ntev thiab mob, nrog mob thiab mob. Cia peb sau ntau cov pathologies, uas cov kev npaj hauv qab ntawm pawg pab pawg no raug pom zoo:
- osteoarthritis;
- rheumatoid kev mob caj dab;
- gout;
- mob taub hau, mob caj pas ;
- kub cev;
- cov kab mob neurological;
- dysmenorrhea;
- hawb pob;
- metastases ntawm pob txha;
- Postoperative mob hlwb;
- inflammatory arthropathy.
Daim ntawv teev cov tshuaj tsis-steroidal anti-inflammatory
Daim ntawv teev cov niaj hnub non-steroidal anti-inflammatory tshuaj yog tam sim no heev thoob plaws. Lawv raug cais raws li cov qauv tshuaj thiab qhov xwm txheej ntawm kev ua ub no. Tsis tas li ntawd, cov ntaub ntawv sib txawv ntawm cov tshuaj uas tsis yog siv tshuaj tua kab mob yog sib faib: cov ntsiav tshuaj, tshuaj ntsiav, tshuaj pleev, cov tshuaj kua roj, kua tshuaj, kua tshuaj, thiab lwm yam tshuaj.
Xav txog cov hom mob NSAIDs tseem ceeb:
- Salicylates:
- Aspirin;
- Daws sib txawv;
- lysine monoacetyl salicylate.
- Indomethacin;
- Sulindak;
- Qhov no yog eelander.
- Diclofenac ;
- Aceclofenac.
- Ibuprofen;
- Ketoprofen;
- Tiaprofenic acid;
- Naproxen;
- Flurbiprofen;
- Fenbufen;
- Fenoprofen;
- Nabumethon.
- Lornoxicam;
- Tenoxicam;
- Piroxicam;
- Meloksikam.
- Rofecoxib;
- Nimesulide;
- Celecoxib.
Los ntawm cov kev npaj rau kev kho mob ntawm kev ua haujlwm, xws li tshuaj Ketorolac, Ketoprofen, Diclofenac, Indomethacin zoo tshaj. Yam khoom zoo tshaj plaws yog Indomethacin, Flurbiprofen, Diclofenac thiab Piroxicam.
Nws yog tsim nyog sau cia tias cov tshuaj non-steroid anti-inflammatory mus muag nyob rau hauv ntau lub npe ntawm cov lag luam. Yog li ntawd, thaum yuav ib yam tshuaj nyob rau hauv lub tsev muag tshuaj, ua ntej ntawm tag nrho cov, ib tug yuav tsum them nyiaj rau lub npe thoob ntiaj teb.
Nonsteroidal anti-inflammatory tshuaj ntawm lub cim tshiab
Nonsteroidal anti-inflammatory tshuaj ntawm lub cim tshiab ua haujlwm ntau dua thiab qhia qhov siab tshaj plaws hauv kev sib piv nrog cov lawv cov neeg ua ntej. Nyob rau hauv cov ntaub ntawv no, zoo tsis muaj phiv los ntawm gastrointestinal ib ntsuj av.
Sawv cev ntawm cov tshuaj tshiab ntawm pawg neeg NSAID yog oxycam.
Cov NSAIDs kuj muaj lawv qhov kev tsis sib haum xeeb:
- erosive thiab raus qhov txhab ntawm cov kab mob plaw;
- cim kev ua txhaum ntawm daim siab thiab lub raum;
- cytopenia;
- cev xeeb tub;
- tus tib neeg tsis txaus ntseeg.